Can You Get a Right Side of a Weak Heart Not Again

Centre failure is a disorder in which the heart is unable to keep upwards with the demands of the trunk, leading to reduced blood menstruation, redundancy (congestion) of blood in the veins and lungs, and/or other changes that may further weaken or stiffen the heart.

  • Centre failure develops when the contracting action or the relaxing action of the heart is inadequate, typically because the heart musculus is weak, stiff, or both.

  • Many disorders that touch on the middle can cause eye failure.

  • Most people take no symptoms at first, and shortness of breath and fatigue develop gradually over days to months.

  • Fluid may accumulate in the lungs, belly, or legs.

  • Doctors usually suspect middle failure on the basis of symptoms, just tests, such equally echocardiography (ultrasound of the middle), are usually done to evaluate heart office.

  • Treatment focuses on treating the disorder causing heart failure, making lifestyle changes, and treating heart failure with drugs or with surgery or other interventions.

About 6.5 million people in the United States have middle failure and about 960,000 new cases occur each year. Worldwide, nearly 26 1000000 people are afflicted. The disorder is likely to become more common because people are living longer and because, in some countries, certain risk factors for heart affliction (such as obesity Obesity Obesity is backlog torso weight. Obesity is influenced by a combination of factors, which commonly results in consuming more calories than the body needs. These factors may include concrete inactivity... read more Obesity , diabetes Diabetes Mellitus (DM) Diabetes mellitus is a disorder in which the body does not produce plenty or respond normally to insulin, causing blood sugar (glucose) levels to be abnormally high. Urination and thirst are... read more , smoking, and loftier blood pressure High Blood Pressure level Loftier blood pressure (hypertension) is persistently high pressure level in the arteries. Often no cause for loftier blood pressure tin can be identified, but sometimes it occurs as a result of an underlying... read more than High Blood Pressure ) are affecting more people.

Heart failure does not mean that the heart has stopped. It ways that the heart cannot keep up with the work required to pump adequate blood to all parts of the trunk (its workload). Withal, this definition is somewhat simplistic. Heart failure is complex, and no simple definition can encompass its many causes, aspects, forms, and consequences.

  • The right side of the centre pumps blood from the veins into the lungs

  • The left side of the heart pumps claret from the lungs out through the arteries to the rest of the trunk

Blood goes out of the centre when the heart musculus contracts (called systole) and comes into the heart when the centre musculus relaxes (chosen diastole). Heart failure develops when the contracting or the relaxing action of the heart is inadequate, typically because the heart musculus is weak, stiff, or both. As a result, blood may not flow out in acceptable amounts. Blood may also build upwards in the tissues, causing congestion. That is why heart failure is sometimes known equally congestive heart failure.

Accumulation of blood coming into the left side of the centre causes congestion in the lungs, making breathing difficult. Accumulation of blood coming into the right side of the centre causes congestion and fluid aggregating in other parts of the body, such equally the legs and the liver. Eye failure usually affects both the correct and left sides of the heart to some caste. Withal, 1 side may exist afflicted by illness more than than the other. In such cases, center failure may be described as right-sided heart failure or left-sided heart failure.

In heart failure, the heart may not pump enough blood to meet the body's demand for oxygen and nutrients, which are supplied past the claret. As a result, arm and leg muscles may tire more apace, and the kidneys may not role unremarkably. The kidneys filter fluid and waste matter products from the claret into the urine, but when the heart cannot pump fairly, the kidneys malfunction and cannot remove excess fluid from the blood. Equally a outcome, the corporeality of fluid in the bloodstream increases, and the workload of the failing middle increases, creating a vicious circle. Thus, middle failure becomes even worse.

The types of center failure are classified by the ejection fraction (EF), which is the percentage of claret pumped out by the center with each vanquish and is a measure of how well the heart is pumping. A normal left ventricle ejects nearly 55 to lx% of the blood in information technology.

In heart failure with reduced ejection fraction (HFrEF—sometimes called systolic eye failure):

  • The heart contracts less forcefully and pumps out a lower percentage of the claret that is returned to information technology. Every bit a effect, more claret remains in the heart. Blood and so accumulates in the lungs, veins, or both.

In heart failure with preserved ejection fraction (HFpEF—sometimes called diastolic center failure):

  • The eye is stiff and does not relax commonly afterward contracting, which impairs its ability to fill up with blood. The centre contracts normally, so it is able to pump a normal proportion of blood out of the ventricles, but the full amount pumped with each contraction may be less. Sometimes the stiff heart compensates for its poor filling past pumping out an even higher proportion of the blood than information technology commonly does. Nonetheless, somewhen, as in systolic center failure, the claret returning to the eye accumulates in the lungs or veins.

Center failure with mid-range ejection fraction (HFmrEF) is a newer concept that includes people whose ejection fraction is somewhere between preserved and reduced ejection fraction.

Heart Failure: Pumping and Filling Problems

Commonly, the eye stretches as it fills with blood (during diastole), then contracts to pump out the blood (during systole). The principal pumping chambers in the heart are the ventricles.

Heart failure due to systolic dysfunction normally develops because the heart cannot contract normally. It may make full with blood, merely the centre cannot pump out as much of the blood it contains considering the muscle is weaker or because a heart valve malfunctions. As a outcome, the amount of blood pumped to the body and to the lungs is reduced, and the ventricle usually enlarges.

Centre failure due to diastolic dysfunction develops considering the heart muscle stiffens (particularly the left ventricle) and may thicken so that the heart cannot fill normally with blood. Consequently, claret backs up in the left atrium and lung (pulmonary) blood vessels and causes congestion. However, the heart may exist able to pump out a normal percent of the claret information technology receives (but the total corporeality pumped out may exist less).

The center chambers always incorporate some claret, but dissimilar amounts of blood may enter or leave the chambers with each heartbeat as indicated past the thickness of the arrows.

Doctors often divide causes of heart failure into

  • Disorders that directly touch the eye (cardiac causes)

  • Disorders of other torso systems that indirectly affect the heart (non-cardiac causes)

Cardiac disorders that cause eye failure may impair the entire middle or one surface area of the heart. In many cases, a combination of factors results in heart failure.

A mutual cardiac crusade of heart failure is

Other cardiac causes of center failure include

  • Myocarditis (inflammation of middle muscle)

  • Some drugs (for case, some chemotherapy drugs)

  • Some toxins (for case, alcohol)

  • Heart valve disorders

  • Disorders that touch the heart'southward electrical conduction organization and cause an abnormal heart rhythm

  • Some genetic disorders

  • Disorders that stiffen the centre

Some drugs used to treat cancer and some toxins (such every bit alcohol) may also damage heart muscle.

Heart failure may issue from disorders that cause the heart'southward walls to stiffen, such equally infiltrations and infections. For case, in amyloidosis Amyloidosis Amyloidosis is a rare disease in which abnormally folded proteins form amyloid fibrils that accumulate in diverse tissues and organs, sometimes leading to organ dysfunction, organ failure, and... read more Amyloidosis , amyloid, an aberrant protein passes into (infiltrates) many tissues in the torso. If amyloid infiltrates the heart's walls, they stiffen, and heart failure results. In tropical countries, infiltration of eye muscle by certain parasites (such as in Chagas affliction Chagas Disease Chagas disease is an infection acquired by the protozoan Trypanosoma cruzi, which is transmitted by the bite of a kissing bug (also called an assassin or Triatominae bug). The protozoa... read more than Chagas Disease ) can cause centre failure, even in young people.

The most common non-cardiac cause of heart failure is

Less mutual non-cardiac causes of middle failure include

  • Loftier blood pressure in arteries to the lungs (pulmonary hypertension, sometimes caused by pulmonary embolism)

  • Anemia

  • Thyroid gland disorders

  • Kidney failure

  • Some drugs

Some drugs, such every bit nonsteroidal anti-inflammatory drugs, may cause the trunk to retain fluid, which increases the workload of the heart and may precipitate heart failure.

The trunk has several mechanisms to compensate for eye failure.

The body's beginning response to stress, including that due to heart failure, is to release the fight-or-flight hormones, epinephrine (adrenaline) and norepinephrine (noradrenaline). For example, these hormones may exist released immediately after a heart set on damages the centre. Epinephrine and norepinephrine cause the heart to pump faster and more than forcefully. They help the heart increase the corporeality of blood pumped out (cardiac output), sometimes to a normal amount, and thus initially assistance compensate for the heart'south impaired pumping ability.

People who do not have heart affliction normally benefit from release of these hormones when more work is temporarily required of the heart. However, for people who accept chronic centre failure, this sustained response increases demands on an already damaged middle. Over time, the center stops responding as well to the hormones, and the increased demands pb to further deterioration of heart office.

Another of the torso's main compensatory mechanisms for the reduced blood flow in center failure is to increase the corporeality of salt and water retained by the kidneys. Retaining salt and h2o instead of excreting it into urine increases the volume of claret in the bloodstream and helps maintain blood pressure. Even so, the larger book of blood besides stretches the heart muscle, enlarging the center chambers, especially the ventricles. At first, the more than the eye muscle is stretched, the more forcefully information technology contracts, which improves middle function. Yet, after a sure amount of stretching, stretching no longer helps but instead weakens the middle's contractions (every bit when a prophylactic band is overstretched). Consequently, heart failure worsens. In addition, salt and water retention increase fluid congestion in organs such as the lungs, leading to worsening symptoms of centre failure.

Some other important compensatory machinery is enlargement of the muscular walls of the ventricles (ventricular hypertrophy). When the heart must work harder, the heart's walls overstate and thicken, as biceps muscles enlarge afterward months of weight training. At commencement, the enlargement allows the heart to maintain the amount of blood information technology pumps out (cardiac output). However, the enlarged and/or thickened middle somewhen becomes stiff, causing or worsening center failure. Also, the enlargement can stretch the heart valve openings, causing them to malfunction, which causes more pumping issues.

Symptoms of heart failure may begin suddenly, especially if the cause is a heart assault. However, most people have no symptoms when the heart first begins to develop bug. Symptoms and so develop gradually over days to months or years. Heart failure may stabilize for periods of time but often progresses slowly and insidiously.

Some common symptoms are

  • Fatigue

  • Inability to exercise or do other activities that require exertion

In older people, heart failure sometimes causes vague symptoms such as sleepiness, confusion, and disorientation.

The severity of heart failure is usually classified based on how well the person is able to acquit out activities of daily life. The New York Heart Association (NYHA) nomenclature remains an important tool for people and their caregivers to understand the severity of the disease and its touch on their life.

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Right-sided middle failure and left-sided heart failure cause dissimilar symptoms. Although both types of heart failure may exist present, the symptoms of failure of one side often predominate. Somewhen, left-sided centre failure causes right-sided failure.

The master symptom of right-sided heart failure is fluid accumulation, leading to swelling (edema Swelling Swelling is due to excess fluid in the tissues. The fluid is predominantly water. Swelling may be widespread or bars to a single limb or office of a limb. Swelling is ofttimes in the feet and... read more Swelling ) in the feet, ankles, legs, lower back, liver, and abdomen. Where the fluid accumulates depends on the amount of excess fluid and the effects of gravity. If a person is standing, fluid accumulates in the legs and anxiety. If a person is lying down, fluid unremarkably accumulates in the lower dorsum. If the amount of fluid is large, fluid besides accumulates in the abdomen. Fluid accumulation in the liver or stomach can cause nausea, bloating, and loss of appetite. Severe right-sided heart failure can result in loss of weight and muscle. This condition is called cardiac cachexia.

Left-sided eye failure leads to fluid accumulation in the lungs, which causes shortness of breath Shortness of Jiff Shortness of breath—what doctors call dyspnea—is the unpleasant sensation of having difficulty breathing. People experience and draw shortness of breath differently depending on the cause... read more Shortness of Breath . At get-go, shortness of breath occurs merely during exertion, but every bit heart failure progresses, it occurs with less and less exertion and eventually occurs even at balance. People with severe left-sided heart failure may be short of breath when lying down (a condition called orthopnea) considering gravity causes more than fluid to move into the lungs. Such people often wake upward, gasping for breath or wheezing (a status called paroxysmal nocturnal dyspnea). Sitting upwards causes some of the fluid to drain to the bottom of the lungs and makes breathing easier. People with left-sided heart failure also experience tired and weak when doing physical activities, because their muscles are not receiving enough claret.

Acute pulmonary edema is a sudden aggregating of a large corporeality of fluid in the lungs. It causes farthermost difficulty breathing, rapid breathing, bluish peel, and feelings of restlessness, anxiety, and suffocation. Some people have severe spasms of the airways (bronchospasms) and wheezing. Acute pulmonary edema is a life-threatening emergency that can occur when people with centre failure develop very high blood force per unit area, have a center attack, or sometimes simply end taking their center failure drugs or eat salty food.

  • Chest ten-ray

  • Electrocardiography (ECG)

  • Echocardiography and sometimes other imaging tests

  • Blood tests

Doctors commonly doubtable eye failure on the basis of symptoms alone. The diagnosis is supported by the results of a physical examination, including a weak, ofttimes rapid pulse, reduced claret force per unit area, abnormal heart sounds and murmurs and fluid aggregating in the lungs both heard through a stethoscope, an enlarged heart, bloated neck veins, an enlarged liver, and swelling in the abdomen or legs.

Procedures to evaluate centre function are normally done. Testing is also needed to identify the cause of heart failure.

A chest ten-ray can show an enlarged heart, and congested blood vessels and fluid accumulation in the lungs.

  • Whether the heart walls are thickened and relax commonly

  • Whether the valves are operation normally

  • Whether contractions are normal

  • Whether whatsoever area of the centre is contracting abnormally

Echocardiography may aid determine whether heart failure is due to systolic or diastolic dysfunction by enabling doctors to gauge the thickness and stiffness of the heart walls and the ejection fraction. The ejection fraction, an important measure out of heart office, is the percentage of blood pumped out by the heart with each beat. A normal left ventricle ejects about 55 to 60% of the blood in it. If the ejection fraction is depression (less than twoscore%), systolic heart failure is confirmed. If the ejection fraction is normal or high in a person who has symptoms of heart failure, diastolic heart failure is probable.

Blood tests are almost always done. Doctors frequently measure natriuretic peptides (NPs). NPs are substances that accumulate in the blood when heart failure is nowadays but not when other disorders that cause shortness of breath are nowadays. Other claret tests may be done to look for disorders that may be causing centre failure.

Other procedures, such as radionuclide imaging Radionuclide Imaging of the Middle In radionuclide imaging, a tiny corporeality of a radioactive substance (radionuclide), called a tracer, is injected into a vein. The amount of radiation the person receives from the radionuclide... read more than , magnetic resonance imaging Magnetic Resonance Imaging (MRI) of the Center With magnetic resonance imaging (MRI), a powerful magnetic field and radio waves are used to produce detailed images of the heart and chest. This expensive and sophisticated procedure is used... read more than (MRI), computed tomography Computed Tomography (CT) of the Eye Computed tomography (CT) may be used to detect structural abnormalities of the middle, the sac that envelops the center (pericardium), major blood vessels, lungs, and supporting structures in... read more , cardiac catheterization with angiography Cardiac Catheterization and Coronary Angiography Cardiac catheterization and coronary angiography are minimally invasive methods of studying the heart and the blood vessels that supply the center (coronary arteries) without doing surgery. These... read more than Cardiac Catheterization and Coronary Angiography , and do (stress) testing Stress Testing Stressing the heart (by practise or by use of stimulant drugs to make the heart beat faster and more forcibly) can help identify coronary avenue disease. In coronary artery disease, blood flow... read more than Stress Testing may be washed to identify the presence or cause of center failure.

Preventing heart failure involves treating disorders that can cause heart failure before they lead to heart failure. Disorders that can be treated include the following:

  • High claret pressure

  • Obesity

  • Obstructive sleep apnea

  • Blockage of a coronary avenue

  • Heart valve disorders

  • Some abnormal heart rhythms

  • Alcoholism

  • Anemia

  • Thyroid disorders

  • Nutrition and lifestyle changes

  • Handling of the crusade of middle failure

  • Drugs

  • Sometimes an implantable cardioverter-defibrillator, cardiac resynchronization therapy, or mechanical circulatory support

  • Sometimes eye transplantation

Treatment of heart failure requires several full general measures, along with handling of the disorder causing center failure, lifestyle changes, and drugs for heart failure.

Although for most people eye failure is a chronic disorder, much can be done to make physical activity more comfy, improve the quality of life, minimize the gamble of sudden worsening (astute heart failure), and prolong life. Affected people and their family members should learn all they can well-nigh center failure because much care occurs at home. In detail, they should know how to recognize the early warning symptoms of worsening centre failure and should be aware of the actions they need to take (for example, reduce table salt intake, take an extra dose of a diuretic, or contact their physician).

Regular communication with health care practitioners and examinations by doctors are critical because center failure can worsen suddenly. For example, nurses may regularly call people who take eye failure to ask most changes in weight and in symptoms. Thus, they can approximate whether people need to see a physician.

People may besides get to specialized middle failure clinics. These clinics have doctors with expertise in heart failure who work closely with particularly trained nurses and other health care practitioners, such equally pharmacists, dietitians, and social workers, to care for people with heart failure by education self-care skills to people and their caregivers. These clinics can also assistance decrease symptoms, reduce hospitalizations, and improve life expectancy by making sure that people receive the well-nigh constructive treatments and by didactics people how to fully participate in their intendance. This intendance complements rather than replaces care provided past primary care doctors.

People with centre failure should always check with their doctor earlier taking a new drug, even a nonprescription drug. Some drugs (including many used to treat arthritis) can cause salt and fluid retentiveness. Other drugs may make the middle office more slowly. Forgetting to have necessary drugs is a common cause of worsening symptoms, and people should be given ways to remind themselves to accept their drugs.

Did You Know...

  • Heart failure is unremarkably a chronic condition, and changes in lifestyle can help people feel and function better.

Changes in lifestyle tin can assistance people with heart failure feel and part better.

People who have eye failure should stay as physically fit equally possible, even if they cannot exercise vigorously. People who have balmy heart failure should follow an do program as prescribed by a physician. People with more astringent heart failure may need to exercise in a cardiovascular rehabilitation facility under the supervision of a trained bellboy.

If people with middle failure are overweight, the heart has to piece of work harder during action, worsening heart failure. Such people should follow a salubrious Weight Loss Diets to accomplish and maintain ideal weight.

Excess salt (sodium) in the nutrition can cause fluid retention, which counteracts drugs given to increase the excretion of water (such as diuretics) and relieve fluid accumulation. Thus, consuming excess salt worsens symptoms. Nearly all people with heart failure should limit their intake of tabular array table salt and salty foods and their utilize of salt in cooking. The sodium content of packaged foods tin be determined by reading the label. People with astringent heart failure are unremarkably given detailed information about how to limit salt intake. Educational activity by a dietitian tin be helpful. People who limit their salt intake can commonly consume a normal amount of water unless fluid retention is severe. Drinking extra amounts of h2o is not recommended.

A simple, reliable way to bank check whether the trunk is retaining fluid is to check body weight daily. Doctors oft enquire people with center failure to weigh themselves as accurately equally possible every 24-hour interval, typically once in the morning, after they arise and urinate and before they consume breakfast. Trends are easier to spot when people weigh themselves at the same time every 24-hour interval, use the same scale, wear a like amount of clothing, and keep a written record of their daily weight. Increases of more than ii pounds (nearly 1 kilogram) per twenty-four hours are early on warning signs of fluid memory. A consequent, rapid weight gain (such as ii pounds per day) is a clue that middle failure is worsening.

Many people who limit their salt intake all the same have swelling. Swollen legs should be kept elevated on a stool when sitting. This position helps the body reabsorb and eliminate the excess fluid. Some people also need to wear full-length supportive stockings that help prevent aggregating of fluid. If fluid accumulates in the lungs, sleeping with several pillows or elevating the head of the bed makes sleeping easier.

Drug treatment of heart failure involves

  • Drugs to help save symptoms: Diuretics Diuretics Heart failure is a disorder in which the centre is unable to keep upwards with the demands of the trunk, leading to reduced claret catamenia, redundancy (congestion) of blood in the veins and lungs, and/or... read more than , nitrates Vasodilators Heart failure is a disorder in which the heart is unable to keep up with the demands of the torso, leading to reduced blood flow, back-up (congestion) of blood in the veins and lungs, and/or... read more , or digoxin Digoxin Heart failure is a disorder in which the centre is unable to proceed upward with the demands of the body, leading to reduced blood menses, back-up (congestion) of claret in the veins and lungs, and/or... read more

  • Drugs to help improve survival: Angiotensin-converting enzyme (ACE) inhibitors Angiotensin-converting enzyme (ACE) inhibitors Center failure is a disorder in which the heart is unable to continue up with the demands of the body, leading to reduced blood menstruation, back-upwardly (congestion) of blood in the veins and lungs, and/or... read more , beta-blockers Beta-blockers Heart failure is a disorder in which the heart is unable to go along upwards with the demands of the body, leading to reduced claret catamenia, back-up (congestion) of claret in the veins and lungs, and/or... read more , aldosterone antagonists Aldosterone antagonists Heart failure is a disorder in which the heart is unable to go on upwardly with the demands of the body, leading to reduced blood flow, back-up (congestion) of blood in the veins and lungs, and/or... read more , angiotensin Two receptor blockers Angiotensin 2 receptor blockers (ARBs) Heart failure is a disorder in which the eye is unable to keep upwards with the demands of the body, leading to reduced blood menstruum, redundancy (congestion) of blood in the veins and lungs, and/or... read more (ARBs), angiotensin receptor/neprilysin inhibitors Angiotensin receptor/neprilysin inhibitors Centre failure is a disorder in which the center is unable to keep up with the demands of the body, leading to reduced blood flow, back-upwards (congestion) of claret in the veins and lungs, and/or... read more (ARNIs), sodium glucose co-transporter 2 inhibitors Sodium glucose co-transporter two inhibitors Middle failure is a disorder in which the eye is unable to continue upwardly with the demands of the body, leading to reduced blood flow, back-up (congestion) of claret in the veins and lungs, and/or... read more than , sinus node inhibitors Sinus node inhibitors Heart failure is a disorder in which the heart is unable to keep up with the demands of the body, leading to reduced blood menstruation, back-up (congestion) of blood in the veins and lungs, and/or... read more

The type of drug used depends on the type of heart failure. In systolic heart failure (HFrEF), all drug classes are helpful. In diastolic heart failure (HFpEF), only ACE inhibitors, ARBs, aldosterone antagonists and beta-blockers are typically used. In HFmrEF, ARNIs may exist helpful.

Information technology is of import for people to take their drugs regularly and exist sure not to let the prescription run out.

Mechanical devices that aid pump blood are used for certain people with very severe centre failure that is not responding to drug therapy. Types of devices include

  • Intra-aortic counterpulsation balloon pump: A sausage-shaped balloon on the end of a catheter is placed in the aorta. A motorcar monitors the middle vanquish and inflates the balloon when the heart relaxes and deflates it when the eye contracts, which makes it easier for the heart to pump blood.

  • Ventricular help devices: Different mechanical pumps tin exist implanted in or near the left or correct ventricle to help the center pump blood.

  • Intravascular assist devices: Modest pumps tin exist implanted within large vessels such as the aorta to help pump blood.

  • Extracorporeal membrane oxygenation (ECMO): A device similar to a heart-lung bypass machine takes blood from a big artery and pumps it past a membrane that allows oxygen into the blood and then pumps information technology back into a large vein.

If heart failure is acquired by a problem with a heart valve, doctors may repair or supplant the valve.

Eye failure that develops or worsens rapidly requires emergency treatment in a infirmary.

If astute pulmonary edema (rapid aggregating of fluid in the lungs) develops, oxygen is given through a face mask. Diuretics given intravenously and other drugs such as nitroglycerin given intravenously or under the tongue can give rapid, dramatic improvement. Morphine relieves the anxiety that usually accompanies acute pulmonary edema simply it too decreases the rate of breathing and is no longer used as ofttimes. If these measures do not adequately improve breathing, a specialized mask to deliver oxygen at controlled pressures may be used or a tube may be inserted into the person's airway so that a mechanical ventilator tin can assist animate.

For people who have severe symptoms and have non responded well to treatments, drugs that are like to epinephrine and norepinephrine (such as dopamine or dobutamine) or other drugs that brand cardiac muscle contract more forcefully (such as milrinone) are sometimes used for a brusk fourth dimension to enhance the pumping function of the heart. These drugs are not useful for long-term treatment.

Life expectancy depends on many factors, including how severe the heart failure is, whether its cause can be corrected, and which handling is used. However, once people accept needed to be hospitalized for heart failure, merely about 1 in 3 live some other 5 years. Nearly half of those who have astringent heart failure live at least two years. Life expectancy does ameliorate with treatment.

The post-obit is an English language-language resource that may be useful. Please note that THE Transmission is non responsible for the content of these resource.

  • American Heart Association: Provides resource and information for people living with heart failure and their families

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Source: https://www.msdmanuals.com/home/heart-and-blood-vessel-disorders/heart-failure/heart-failure-hf

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